1H-Imidazole, 2-fluoro- - Names and Identifiers
1H-Imidazole, 2-fluoro- - Physico-chemical Properties
Molecular Formula | C3H3FN2
|
Molar Mass | 86.07 |
Density | 1.320±0.06 g/cm3(Predicted) |
Boling Point | 224.6±23.0 °C(Predicted) |
pKa | 11.41±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
1H-Imidazole, 2-fluoro- - Risk and Safety
1H-Imidazole, 2-fluoro- - Introduction
2-fluoro-1H-Imidazole is an organic compound with the formula C3H3FN2, which corresponds to the structure of 2-fluoro-1H-imidazole. The following is a description of the nature, use, preparation and safety information of 2-fluoro-1H-Imidazole:
Nature:
-Appearance: Colorless solid
-melting point: 71-73 ℃
-Boiling point: 195-197 ℃
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide
-Stability: 2-fluoro-1H-Imidazole is stable to heat and light
Use:
-Chemical synthesis: 2-fluoro-1H-Imidazole can be used as an intermediate for the synthesis of other compounds. It is often used in organic synthesis reactions, such as the preparation of drugs, dyes and ligands.
-Biological research: 2-fluoro-1H-Imidazole also has some applications in biological research, such as the study of protein and nucleic acid interactions, enzyme reactions, etc.
Preparation Method:
2-fluoro-1H-Imidazole can be prepared in a variety of ways. The following is one of the commonly used preparation methods:
The reaction of 1H-imidazole with hydrogen fluoride is usually carried out in a water-insoluble solvent. The reaction can be carried out using ammonium fluoride or imidazole triflate as the fluorine source and at lower temperatures.
Safety Information:
- 2-fluoro-1H-Imidazole may be irritating to the eyes, skin and respiratory system, so wear appropriate protective equipment (such as gloves, glasses, protective mask, etc.).
-During storage and handling, it should be stored separately from oxidants, strong acids and strong bases to avoid reaction with these substances.
-Dispose of 2-fluoro-1H-Imidazole in accordance with local environmental regulations. Do not discharge it into water or the natural environment to avoid pollution to the environment.
In view of the complexity and potential hazards of chemicals, please read and follow the relevant safety and operating procedures before use, and consult a professional if necessary.
Last Update:2024-04-09 20:49:11